Prolotherapy is often considered the original regenerative medicine treatment, as it was first developed in the 1950s to treat ongoing painful musculoskeletal conditions. At New England Stem Cell Institute, Dr. Paul Tortland and Dr. Jeffrey LaVallee have been using prolotherapy to reduce pain and promote healing since 1995, longer than almost all medical practices in the United States.
Sometimes referred to as “proliferative therapy,” prolotherapy is a form of regenerative medicine that stimulates your body’s natural healing powers. The treatment involves an injection made up of dextrose (a type of sugar) and Novocaine™. The sugar in the injection mildly irritates your tissue, which tricks your body into thinking it’s been injured. This then signals your body to send healing cells to repair the damage.
Prolotherapy was invented in the 1950s by Ohio surgeon Dr. George Hackett. He used it successfully to treat chronic back pain. In one sense, prolotherapy may be considered the “original” regenerative medicine treatment.
Prolotherapy stimulates the repair of damaged tissue as well as the production of new tissue, but it does NOT cause scar tissue formation.
Prolozone is a variant of prolotherapy. Invented by regenerative medicine and anti-aging physician Dr. Frank Shallenberger, Prolozone modifies the basic prolotherapy dextrose-Novocaine solution by adding various vitamins and homeopathic ingredients that can help provide nutrition for the cells during healing.
In addition, Prolozone® also involves injecting the damaged area with a mixture of oxygen and ozone gases immediately after the liquid solution. Oxygen and ozone also support cell function to stimulate healing.
The team at the New England Stem Cell Institute offers prolotherapy as a treatment to manage many common musculoskeletal conditions, including:
Because the injection contains an anesthetic and all-natural ingredients, prolotherapy and Prolozone® are considered very safe treatments with minimal side effects or risks.
Your physician at the New England Stem Cell Institute will discuss with you whether prolotherapy or Prolozone is the best treatment option for you.
First, prolotherapy and Prolozone® don’t require drawing blood or harvesting stem cells from bone marrow or fat. So, treatments are much quicker and don’t require more invasive harvesting techniques. And, these treatments are also less expensive since no cells need to be obtained. Prolotherapy and Prolozone® are generally slightly milder or less aggressive treatments compared to either PRP or stem cells. For patients where a less robust treatment is needed, prolotherapy or Prolozone® may be more appropriate. However, because they are less potent, more treatments are usually needed. In our experience, one PRP treatment is roughly equivalent to 2-3 prolotherapy or Prolozone® treatments.